Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383177 | 0.80 | HDAC6 (0.49) | HDAC3HDAC1HDAC6MLYCDHDAC4 | |
| SCHEMBL3381027 | 0.76 | HDAC6 (0.53) | HDAC3HDAC1HDAC6MLYCDHDAC4 | |
| SCHEMBL3379859 | 0.74 | HDAC6 (0.55) | HDAC3HDAC1HDAC6MLYCDHDAC4 | |
| SCHEMBL4432362 | 0.74 | HDAC3 (0.40) | HDAC3HDAC1HDAC2HDAC6MLYCD | |
| SCHEMBL5091808 | 0.73 | HDAC6 (0.38) | HDAC3HDAC1HDAC2HDAC6MLYCD | |
| SCHEMBL4429620 | 0.71 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8EPHX1 | |
| SCHEMBL9431190 | 0.71 | TDP1 (0.52) | HDAC3HDAC1HDAC6MLYCDHDAC4 | |
| SCHEMBL24256302 | 0.71 | HDAC3 (0.32) | HDAC3HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL5091803 | 0.69 | CYP2D6 (0.41) | HDAC3HDAC1HDAC6MLYCDHDAC4 | |
| SCHEMBL5300088 | 0.69 | GAA (0.45) | HDAC3HDAC1HDAC2HDAC8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137651-A | Pyridazinone compounds | ANADYS PHARMACEUTICALS INC (US) | 2008-03-05 | — | — | CN | disclosed |