Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.35 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22265191 | 0.88 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL16985411 | 0.82 | — | — | |
| SCHEMBL16985363 | 0.82 | — | — | |
| SCHEMBL3936878 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28104876 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL28105006 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL16975421 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL23929455 | 0.73 | — | — | |
| SCHEMBL516648 | 0.73 | — | — | |
| SCHEMBL12206943 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784534-A | Process for preparing oxazoline protected aminodiol compounds useful as intermediates of florfenicol | SCHERING PLOUGH LTD | 2010-07-21 | — | — | CN | claimed |
| CN-101300227-B | Process for preparing ester oxazolidine compounds and their conversion to florfenicol | SCHERING PLOUGH LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-102131772-A | Process for the preparation of oxazoline-protected aminodiol compounds useful as intermediates for florfenicol | INTERVET INT BV | 2011-07-20 | — | — | CN | disclosed |
| CN-101796037-A | Processes for preparing oxazolidine-and oxazolidinone-aminodiols and related intermediates | INTERVET INTERMATONAL B V | 2010-08-04 | — | — | CN | disclosed |
| CN-101300227-A | Process for preparing ester * oxazolidine compound and its conversion to florfenicol | SCHERING PLOUGH LTD (CH) | 2008-11-05 | — | — | CN | disclosed |
| CN-101300237-A | Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to florfenicol | SCHERING PLOUGH LTD (CH) | 2008-11-05 | — | — | CN | disclosed |
| CN-101300238-A | Improved process for the preparation of * oxazolidine protected aminodiol compounds useful as florfenicol intermediates | SCHERING PLOUGH LTD (CH) | 2008-11-05 | — | — | CN | disclosed |