SCHEMBL27720138

SCHEMBL27720138

C=CC(=O)OCO[Si](CCCCCCC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 2/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
LMNA P02545 1/20 0.37
THRB P10828 3/20 0.35
THRA P10827 1/20 0.35
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FAAH O00519 1/20 0.33
EPHX1 P07099 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27985885 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27846911 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27720159 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27985535 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27816094 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27985914 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL28238283 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL28207620 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL27743751 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20
SCHEMBL28229095 1.00 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003920-A Aligning agent for liquid crystal, the manufacturing method of liquid crystal orientation film and liquid crystal display element 奇美实业股份有限公司 2019-07-12 CN disclosed
CN-107001583-B Photocurable and thermosetting resin composition, cured product, and laminate 株式会社钟化 2019-06-18 CN disclosed
CN-109890344-A The dental adhesive of subpackage type 可乐丽则武齿科株式会社 2019-06-14 CN disclosed
CN-109715694-A Hollow particles and uses thereof 积水化成品工业株式会社 2019-05-03 CN disclosed
CN-106132686-B Laminated body, transparent conductive laminate and touch panel 东丽株式会社 2018-02-13 CN disclosed
CN-104232107-B The manufacture method of aligning agent for liquid crystal, phase retardation film and phase retardation film JSR株式会社 2017-09-01 CN disclosed
CN-107001583-A Photocurable and thermosetting resin composition, cured product, and laminate 株式会社钟化 2017-08-01 CN disclosed
CN-105324407-B Active energy ray-curable composition 株式会社钟化 2017-07-28 CN disclosed
CN-104822522-B Hard coat film and transparent and electrically conductive film 东丽薄膜先端加工股份有限公司 2017-03-08 CN disclosed
CN-106324911-A El polymer composition for viewing angle compensation film, viewing angle compensation film, manufacturing method and application of the viewing angle compensation film JSR株式会社 2017-01-11 CN disclosed
CN-101451050-B Pressure sensitive adhesive tape NITTO DENKO CORP 2013-07-10 CN disclosed
CN-103189465-A Water-dispersible oil-resistant adhesive composition, oil-resistant adhesive sheet, method of adhesion, and oil-resistant adhesive structure NITTO DENKO CORP 2013-07-03 CN disclosed
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102591071-A Process for producing liquid crystal display device, the liquid crystal display device, and liquid crystal aligning agent JSR CORP 2012-07-18 CN disclosed
CN-102483469-A Reflection prevention member and manufacture method for the same TORAY INDUSTRIES 2012-05-30 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
CN-101163766-B Adhesive composition KURARAY MEDICAL INC 2011-05-04 CN disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed
CN-101451050-A Pressure sensitive adhesive tape NITTO DENKO CORP (JP) 2009-06-10 CN disclosed
CN-101163766-A Adhesive composition KURARAY MEDICAL INC (JP) 2008-04-16 CN disclosed