SCHEMBL27720209

SCHEMBL27720209

C#Cc1c(C(=O)O)ccc(C(=O)O)c1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.37
EPHX2 P34913 4/20 0.36
SERPINE1 P05121 2/20 0.36
HIF1A Q16665 1/20 0.34
EPAS1 Q99814 1/20 0.34
RARA P10276 2/20 0.34
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
LMNA P02545 1/20 0.34
P2RX7 Q99572 1/20 0.34
KDM5A P29375 1/20 0.34
KDM5B Q9UGL1 1/20 0.34
STS P08842 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149907 0.84 KDM4E (0.45) KDM4ENPC1EPHX2SERPINE1HIF1A
Hydrochloric Acid SCHEMBL5000857 0.80 RARG (0.36) KDM4ENPC1EPHX2SERPINE1HIF1A
SCHEMBL5834020 0.79 KDM4E (0.51) KDM4ENPC1EPHX2SERPINE1HIF1A
SCHEMBL27716784 0.78 RARG (0.37) KDM4EEPHX2SERPINE1HIF1AEPAS1
SCHEMBL27716783 0.78 KDM4E (0.35) KDM4ENPC1EPHX2SERPINE1HIF1A
Hydrochloric Acid SCHEMBL5000860 0.76 SERPINE1 (0.41) KDM4ENPC1EPHX2SERPINE1HIF1A
SCHEMBL18040210 0.75 SELL (0.47) KDM4ENPC1EPHX2SERPINE1HIF1A
SCHEMBL8132446 0.74 NPC1 (0.41) KDM4ENPC1EPHX2SERPINE1HIF1A
SCHEMBL18040209 0.73 KDM4E (0.49) KDM4EEPHX2SERPINE1HIF1AEPAS1
SCHEMBL27759390 0.73 NPC1 (0.40) KDM4ENPC1EPHX2SERPINE1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101268119-B Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-08-17 CN disclosed
CN-101128514-B Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-05-25 CN disclosed
CN-101268119-A Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-09-17 CN disclosed
CN-101128514-A Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-02-20 CN disclosed