Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 1/20 | 0.55 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 10/20 | 0.53 |
| ▸ | CDK1 | P06493 | 6/20 | 0.53 |
| ▸ | AURKA | O14965 | 4/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286493 | 0.91 | PAK4 (0.53) | PAK4PAK1MAPTKDM4EALDH1A1 | |
| SCHEMBL2286333 | 0.89 | CDK2 (0.64) | CDK2CDK1AURKAAURKBMAPK1 | |
| SCHEMBL27741376 | 0.89 | CDK2 (0.59) | MAPTSMN1; SMN2CDK2CDK1AURKA | |
| SCHEMBL27741378 | 0.88 | CDK4 (0.55) | PAK4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2282854 | 0.88 | PAK4 (0.51) | PAK4PAK1MAPTKDM4EALDH1A1 | |
| SCHEMBL2283651 | 0.86 | PAK4 (0.55) | PAK4PAK1MAPTKDM4EALDH1A1 | |
| SCHEMBL27720301 | 0.86 | CDK2 (0.49) | PAK4ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2285488 | 0.86 | CDK2 (0.50) | PAK4HPGDHTTCDK2CDK1 | |
| SCHEMBL2283561 | 0.86 | CDK2 (0.50) | CDK2CDK1AURKAAURKBJAK2 | |
| SCHEMBL27720314 | 0.85 | CDK2 (0.57) | PAK4SMN1; SMN2CDK2CDK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |