Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.55 |
| ▸ | CDK4 | P11802 | 17/20 | 0.53 |
| ▸ | AURKA | O14965 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 4/20 | 0.52 |
| ▸ | CDK7 | P50613 | 4/20 | 0.52 |
| ▸ | CDK9 | P50750 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 3/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | ABL2 | P42684 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772313 | 0.92 | CDK2 (0.67) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27720293 | 0.88 | CDK2 (0.51) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27741332 | 0.86 | CDK2 (0.51) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL28772325 | 0.85 | CDK2 (0.74) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL2076359 | 0.84 | CDK2 (0.60) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27720287 | 0.83 | CDK2 (0.74) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL2286557 | 0.82 | CDK2 (0.56) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27720262 | 0.82 | CDK2 (0.76) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27741363 | 0.82 | CDK2 (0.53) | CDK2CDK4AURKACDK1CDK7 | |
| SCHEMBL27741459 | 0.81 | CDK2 (0.73) | CDK2CDK4AURKACDK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |