Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 13/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720924 | 0.91 | NR1H2 (0.35) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL28768677 | 0.89 | NR1H2 (0.34) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL27720683 | 0.87 | NR1H2 (0.38) | NR1H2BRD4CREBBPNR1H3 | |
| SCHEMBL27700243 | 0.87 | NR1H2 (0.36) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL28772263 | 0.86 | ABCB1 (0.34) | — | |
| SCHEMBL27720788 | 0.85 | EED (0.35) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL3046133 | 0.84 | NR1H2 (0.34) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL28943660 | 0.83 | HRH3 (0.38) | TBK1 | |
| SCHEMBL27700250 | 0.83 | NR1H2 (0.36) | NR1H2BRD4CREBBPNR1H3TBK1 | |
| SCHEMBL27700218 | 0.83 | NR1H2 (0.33) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |