⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL14829309 | 0.76 | — | — | |
| SCHEMBL4077679 | 0.76 | — | — | |
| SCHEMBL27709980 | 0.70 | — | — | |
| SCHEMBL14135180 | 0.68 | — | — | |
| SCHEMBL8345021 | 0.66 | — | — | |
| SCHEMBL255876 | 0.65 | — | — | |
| SCHEMBL27768985 | 0.65 | — | — | |
| SCHEMBL1232382 | 0.65 | — | — | |
| SCHEMBL2016827 | 0.65 | — | — | |
| SCHEMBL1254660 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255132-B | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE | 2010-12-15 | — | — | CN | claimed |
| CN-101317845-A | Pharmaceutical use of 6-aryl substituted pyridine compounds | UNIV ZHEJIANG (CN) | 2008-12-10 | — | — | CN | claimed |
| CN-101255132-A | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE (CN) | 2008-09-03 | — | — | CN | claimed |
| CN-101255132-B | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE | 2010-12-15 | — | — | CN | disclosed |
| CN-101255132-B | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE | 2010-12-15 | — | — | CN | disclosed |
| CN-101440061-B | Arylpyridone derivatives with acetylcholine esterase inhibition activity | WENZHOU MEDICAL COLLEGE | 2010-12-08 | — | — | CN | disclosed |
| CN-101440061-B | Arylpyridone derivatives with acetylcholine esterase inhibition activity | WENZHOU MEDICAL COLLEGE | 2010-12-08 | — | — | CN | disclosed |
| CN-101284007-B | Pharmaceutical use of aryl group substituted pyridone derivates in preparing medicine for tumour | UNIV ZHEJIANG | 2010-11-17 | — | — | CN | disclosed |
| CN-101317845-B | Pharmaceutical use of 6-aryl substituted pyridine compounds | UNIV ZHEJIANG | 2010-09-29 | — | — | CN | disclosed |
| CN-101440061-A | Arylpyridone derivatives with acetylcholine esterase inhibition activity | WENZHOU MEDICAL COLLEGE (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-101440061-A | Arylpyridone derivatives with acetylcholine esterase inhibition activity | WENZHOU MEDICAL COLLEGE (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-101317845-A | Pharmaceutical use of 6-aryl substituted pyridine compounds | UNIV ZHEJIANG (CN) | 2008-12-10 | — | — | CN | disclosed |
| CN-101284007-A | Pharmaceutical use of aryl group substituted pyridone derivates | UNIV ZHEJIANG (CN) | 2008-10-15 | — | — | CN | disclosed |
| CN-101255132-A | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE (CN) | 2008-09-03 | — | — | CN | disclosed |
| CN-101255132-A | 6-aryl-3-substituted methylene-pyridinone derivatives and uses thereof | WENZHOU MEDICAL COLLEGE (CN) | 2008-09-03 | — | — | CN | disclosed |