SCHEMBL27720784

SCHEMBL27720784

CC(CO)C(N)c1ccc2[nH]c(-c3ccc(Cl)c4c3C(C(=O)C3NCc5c(Cl)ccc(-c6cc7cc(C(N)C(C)CO)ccc7[nH]6)c53)NC4)cc2c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.32
PPARG P37231 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27720777 0.85 FFAR1 (0.34) FFAR1PPARG
SCHEMBL27720925 0.84 FFAR1 (0.33) FFAR1PPARGHDAC6
SCHEMBL27700230 0.83 FFAR1 (0.33) FFAR1PPARG
SCHEMBL27700343 0.83 FFAR1 (0.32) FFAR1PPARG
SCHEMBL27720750 0.82 FFAR1 (0.31) FFAR1
SCHEMBL27720677 0.80 FFAR1 (0.35) FFAR1PPARG
SCHEMBL27720753 0.79 FFAR1 (0.34) FFAR1PPARG
SCHEMBL27700174 0.79 GRIN2D (0.35) FFAR1PPARG
SCHEMBL27720749 0.78 CYP51A1 (0.38) FFAR1
SCHEMBL27720815 0.78 HDAC6 (0.36) FFAR1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163675-A Nitrogen-containing heterocyclic compound KYOWA HAKKO KOGYO KK (JP) 2008-04-16 CN disclosed