Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720792 | 0.93 | TTK (0.36) | NR1H2NAMPTNR1H3TTKBRD4 | |
| SCHEMBL28772320 | 0.87 | TTK (0.35) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL27700210 | 0.85 | NR1H2 (0.33) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL27720813 | 0.85 | NR1H2 (0.35) | NR1H2NR1H3BRD4CREBBP | |
| SCHEMBL28772268 | 0.82 | BRD4 (0.35) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL27700223 | 0.80 | NR1H2 (0.34) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL27700173 | 0.79 | NR1H2 (0.35) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL27700204 | 0.79 | BRD4 (0.34) | NR1H2NR1H3TTKBRD4CREBBP | |
| SCHEMBL28768687 | 0.78 | BRD4 (0.34) | NR1H2NR1H3BRD4CREBBP | |
| SCHEMBL27700283 | 0.78 | NR1H2 (0.34) | NR1H2NR1H3BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |