Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27742718 | 0.90 | TDP1 (0.41) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27779744 | 0.90 | TDP1 (0.41) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27722913 | 0.90 | TDP1 (0.50) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27663311 | 0.88 | TDP1 (0.45) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL28050472 | 0.88 | TDP1 (0.45) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27702406 | 0.88 | TDP1 (0.48) | TDP1ANPEPERAP2ITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27923537 | 0.88 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27765046 | 0.87 | TDP1 (0.43) | TDP1ANPEPERAP2KDM1ASLC6A1 | |
| Tert-Butyl Formate SCHEMBL27698140 | 0.85 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27562936 | 0.83 | TDP1 (0.43) | TDP1ANPEPERAP2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437153-A | hepatitis B core protein allosteric modulators | UNIV INDIANA RES & TECH CORP | 2019-11-12 | — | — | CN | disclosed |
| CN-108884070-A | PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108884083-A | Benzo [ B ] furans as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-106413402-A | Hepatitis b core protein allosteric modulators | 美国印第安纳大学研究和技术公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105473575-A | Benzimidazolyl-methylurea derivatives as ALX receptor agonists | ACTELION PHARMACEUTICALS LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105339371-A | Thieno[3,2-d]pyrimidine-6-carboxamides and analogues as sirtuin modulators | GLAXOSMITHKLINE LLC | 2016-02-17 | — | — | CN | disclosed |
| CN-104968656-A | AUTOTAXIN INHIBITORS | NOVARTIS AG | 2015-10-07 | — | — | CN | disclosed |
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | disclosed |
| CN-102232076-B | Pyrrolopyrazinyl urea kinase inhibitors | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |
| CN-102164920-B | Alkylthiazole carbamate derivatives, method for the production thereof and use thereof as FAAH enzyme inhibitors | SANOFI AVENTIS | 2013-12-25 | — | — | CN | disclosed |
| CN-102232076-A | Pyrrolopyrazinyl urea kinase inhibitors | HOFFMANN LA ROCHE | 2011-11-02 | — | — | CN | disclosed |
| CN-102164920-A | Alkylthiazole carbamate derivatives, method for the production thereof and use thereof as FAAH enzyme inhibitors | SANOFI AVENTIS | 2011-08-24 | — | — | CN | disclosed |
| CN-101309918-B | [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-amine derivatives as ikk-beta inhibitors for the treatment of cancer and inflammatory diseases | LILLY CO ELI | 2010-12-29 | — | — | CN | disclosed |
| CN-101528680-A | New phenylsulfamoyl benzamide derivatives as bradykinin antagonists | RICHTER GEDEON NYRT (HU) | 2009-09-09 | — | — | CN | disclosed |
| CN-101309918-A | [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-amine derivatives as ikk-beta inhibitors for the treatment of cancer and inflammatory diseases | LILLY CO ELI (US) | 2008-11-19 | — | — | CN | disclosed |
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |