Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 7/20 | 0.37 |
| ▸ | NPY1R | P25929 | 5/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28712062 | 0.95 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL9237239 | 0.95 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL288133 | 0.95 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| Hydrochloric Acid SCHEMBL8040222 | 0.93 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| Hydrochloric Acid SCHEMBL8039440 | 0.93 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL3133848 | 0.92 | DPP7 (0.41) | DPP7OTCMEN1CYP1A2KMT2A | |
| SCHEMBL29106719 | 0.92 | DPP7 (0.41) | DPP7OTCMEN1CYP1A2KMT2A | |
| SCHEMBL16194087 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL7061485 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL28111481 | 0.90 | DPP7 (0.40) | DPP7OTCMEN1KMT2ADDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103695343-B | One strain utilize arginine and do not accumulate citrulline addicted to salt tetrads | JIANGNAN UNIVERSITY (CN) | 2015-09-30 | — | — | CN | disclosed |
| CN-104130996-A | Arginine deiminase mutant from arthritis-type mycoplasma and application thereof | SHANGHAI INST PHARM INDUSTRY | 2014-11-05 | — | — | CN | disclosed |
| CN-103695343-A | Tetragenococcus halophilus using arginine without accumulating citrulline | UNIV JIANGNAN | 2014-04-02 | — | — | CN | disclosed |
| CN-103374552-A | PHF 8 (Plant Homedomain Finger Protein 8) protein fragment as well as prokaryotic expression and purification method and antibody thereof | SHANGHAI INST BIOL SCIENCES | 2013-10-30 | — | — | CN | disclosed |
| CN-101163497-B | Erythrocytes containing arginine deiminase | ERYTECH PHARMA | 2012-12-19 | — | — | CN | disclosed |
| CN-101792752-A | Metarginase and recombination expression method and use thereof | GUANGZHOU HUAYIN PHARMACEUTICAL TECHNOLOGY CO LTD | 2010-08-04 | — | — | CN | disclosed |
| CN-101163497-A | Use of erythrocytes containing arginine deiminase for preparing a drug to decrease the in vivo plasma concentration of arginine | ERYTECH PHARMA (FR) | 2008-04-16 | — | — | CN | disclosed |