Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703359 | 0.93 | CHEK1 (0.79) | CHEK1KCNH2 | |
| SCHEMBL27723942 | 0.89 | CHEK1 (0.74) | CHEK1KCNH2 | |
| SCHEMBL4353896 | 0.89 | CHEK1 (0.86) | CHEK1KCNH2 | |
| SCHEMBL3069698 | 0.88 | CHEK1 (1.00) | CHEK1KCNH2 | |
| SCHEMBL3064124 | 0.84 | CHEK1 (0.79) | CHEK1KCNH2 | |
| SCHEMBL3064132 | 0.84 | CHEK1 (0.79) | CHEK1KCNH2 | |
| SCHEMBL3064129 | 0.84 | CHEK1 (0.79) | CHEK1KCNH2 | |
| SCHEMBL3083529 | 0.83 | CHEK1 (0.79) | CHEK1KCNH2 | |
| SCHEMBL4349276 | 0.81 | CHEK1 (1.00) | CHEK1KCNH2 | |
| SCHEMBL3082469 | 0.79 | CHEK1 (0.79) | CHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189243-A | Substituted heterocycles and their use as CHK1, PDK1 and PAK inhibitors | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | CN | disclosed |