Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703395 | 0.94 | CNR1 (0.42) | EPHX2CNR1POLBCYP3A4PTGIR | |
| SCHEMBL28769146 | 0.94 | NPC1 (0.34) | EPHX2CNR1POLBALDH1A1CNR2 | |
| SCHEMBL27723970 | 0.93 | TAAR1 (0.36) | EPHX2CNR1POLBCYP3A4CNR2 | |
| SCHEMBL27703389 | 0.93 | CNR1 (0.33) | EPHX2CNR1POLBCNR2MEN1 | |
| SCHEMBL28773084 | 0.92 | EPHX2 (0.39) | EPHX2CNR1CYP3A4PTGIRALDH1A1 | |
| SCHEMBL27703386 | 0.92 | CYP3A4 (0.38) | EPHX2CNR1POLBCYP3A4PTGIR | |
| SCHEMBL27703392 | 0.92 | POLB (0.33) | EPHX2CNR1POLBALDH1A1CTDSP1 | |
| SCHEMBL27703435 | 0.92 | CHRM5 (0.36) | EPHX2CNR1POLBCYP3A4ALDH1A1 | |
| SCHEMBL27703379 | 0.91 | EPHX2 (0.38) | EPHX2CNR1POLBCYP3A4PTGIR | |
| SCHEMBL27724115 | 0.91 | CYP3A4 (0.35) | EPHX2POLBCYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | claimed |
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | disclosed |