Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728105 | 0.87 | CYP2A6 (0.57) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL5434549 | 0.83 | NR4A2 (0.69) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL2085712 | 0.83 | NR4A2 (0.69) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL1557691 | 0.82 | NR4A2 (0.63) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL31127577 | 0.82 | NR4A2 (0.63) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL27723109 | 0.81 | F7 (0.71) | NR4A2GPR84GABRA1GABRB1GABRA3 | |
| SCHEMBL27651981 | 0.81 | NR4A2 (0.63) | NR4A2 | |
| SCHEMBL28940822 | 0.81 | HPGD (0.49) | NR4A2GPR84 | |
| SCHEMBL27501693 | 0.81 | KDM4E (0.59) | GPR84SMN1; SMN2 | |
| SCHEMBL4685934 | 0.80 | NR4A2 (0.65) | NR4A2GPR84GABRA1GABRB1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-101277695-B | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-12-14 | — | — | CN | disclosed |
| CN-101484159-A | Method of modulating neurite outgrowth by the use of a galanin-3 receptor antagonist | HELICON THERAPEUTICS INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-101277695-A | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2008-10-01 | — | — | CN | disclosed |