Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGFR | P43088 | 2/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292949 | 0.83 | PTGER3 (0.60) | EGFRAKR1C3AKR1C2PTGER3PTGER2 | |
| SCHEMBL17802340 | 0.82 | PTGER1 (0.55) | AKR1C3AKR1C2PTGER3PTGER2PTGER1 | |
| SCHEMBL2467808 | 0.81 | PELI1 (0.62) | PTGER3PTGER2PTGER1PTGER4HDAC8 | |
| SCHEMBL2467811 | 0.81 | PELI1 (0.62) | PTGER3PTGER2PTGER1PTGER4HDAC8 | |
| SCHEMBL28198810 | 0.79 | HDAC8 (0.50) | PTGER3PTGER2PTGER1PTGER4LTB4R | |
| SCHEMBL5425639 | 0.79 | PTGER3 (0.56) | PTGER3PTGER2PTGER1PTGER4HDAC8 | |
| SCHEMBL28198808 | 0.79 | HDAC8 (0.50) | PTGER3PTGER2PTGER1PTGER4LTB4R | |
| SCHEMBL5425644 | 0.79 | PTGER3 (0.56) | PTGER3PTGER2PTGER1PTGER4HDAC8 | |
| Methyl Alcohol SCHEMBL11871952 | 0.78 | PELI1 (0.59) | PTGER3PTGER2PTGER1PTGER4HDAC8 | |
| SCHEMBL2433472 | 0.78 | PTGER3 (0.66) | PTGER3PTGER2PTGER1PTGER4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993051-A | Biphenyl and naphthyl-phenyl hydroxamic acid derivatives | SIGMA TAU IND FARMACEUTI | 2013-03-27 | — | — | CN | disclosed |
| CN-101198586-A | Biphenyl and naphthyl-phenyl hydroxamic acid derivatives | SIGMA TAU IND FARMACEUTI (IT) | 2008-06-11 | — | — | CN | disclosed |