Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.69 |
| ▸ | SRC | P12931 | 3/20 | 0.56 |
| ▸ | MAP3K8 | P41279 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896455 | 0.89 | EGFR (0.85) | EGFRERBB2SRC | |
| Hydrochloric Acid SCHEMBL2843055 | 0.88 | EGFR (0.83) | EGFRERBB2SRC | |
| Hydrochloric Acid SCHEMBL2840495 | 0.88 | EGFR (0.83) | EGFRERBB2SRC | |
| SCHEMBL2574073 | 0.87 | EGFR (0.85) | EGFRERBB2SRC | |
| Hydrochloric Acid SCHEMBL2052299 | 0.86 | EGFR (0.84) | EGFRERBB2SRC | |
| SCHEMBL27728120 | 0.86 | EGFR (0.71) | EGFRERBB2SRCMAP3K8 | |
| SCHEMBL2023939 | 0.86 | EGFR (0.69) | EGFRERBB2SRCMAP3K8 | |
| Hydrochloric Acid SCHEMBL13505731 | 0.85 | EGFR (0.68) | EGFRERBB2SRCMAP3K8 | |
| SCHEMBL14854749 | 0.84 | EGFR (0.66) | EGFRERBB2SRCMAP3K8 | |
| SCHEMBL3600034 | 0.84 | EGFR (0.72) | EGFRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223143-A | 3-cyanoquinoline inhibitors of TPL2 kinase and methods of making and using the same | WYETH CORP (US) | 2008-07-16 | — | — | CN | disclosed |