Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 20/20 | 1.00 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.74 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.74 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.74 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707332 | 0.93 | MAP3K8 (0.87) | MAP3K8CAMK2BCAMK2GCAMK2DCAMK2A | |
| SCHEMBL27728235 | 0.90 | MAP3K8 (0.84) | MAP3K8CAMK2BCAMK2GCAMK2DCAMK2A | |
| SCHEMBL27707476 | 0.90 | MAP3K8 (0.84) | MAP3K8 | |
| SCHEMBL27728161 | 0.89 | MAP3K8 (1.00) | MAP3K8CAMK2BCAMK2GCAMK2DCAMK2A | |
| SCHEMBL4962272 | 0.89 | MAP3K8 (0.88) | MAP3K8CAMK2BCAMK2GCAMK2DCAMK2A | |
| SCHEMBL27707365 | 0.89 | MAP3K8 (0.83) | MAP3K8CAMK2BCAMK2GCAMK2DCAMK2A | |
| SCHEMBL4961801 | 0.89 | MAP3K8 (1.00) | MAP3K8 | |
| SCHEMBL31212691 | 0.89 | MAP3K8 (1.00) | MAP3K8 | |
| SCHEMBL6071565 | 0.88 | MAP3K8 (1.00) | MAP3K8 | |
| SCHEMBL27728133 | 0.88 | MAP3K8 (0.88) | MAP3K8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223143-A | 3-cyanoquinoline inhibitors of TPL2 kinase and methods of making and using the same | WYETH CORP (US) | 2008-07-16 | — | — | CN | disclosed |