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Sugi Predict / Compounds / SCHEMBL27728192

SCHEMBL27728192

SCHEMBL27728192

NCc1cc(Br)c(NC(=O)c2cc(C(F)(F)F)nn2-c2ncccc2Cl)c(N(N)C=O)c1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KLKB1 P03952 17/20 0.41
▸ F2 P00734 1/20 0.37
▸ F10 P00742 1/20 0.37
▸ PRSS1 P07477 1/20 0.37
▸ PRSS2 P07478 1/20 0.37
▸ PRSS3 P35030 1/20 0.37
▸ CARM1 Q86X55 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28777101 0.91 F10 (0.35) KLKB1F10CARM1
SCHEMBL27727946 0.87 KLKB1 (0.47) KLKB1F2F10PRSS1PRSS2
SCHEMBL28777098 0.86 KLKB1 (0.41) KLKB1F2F10CARM1
SCHEMBL27727982 0.85 KLKB1 (0.47) KLKB1
SCHEMBL28777123 0.85 KLKB1 (0.41) KLKB1F2F10PRSS1CARM1
SCHEMBL27728197 0.85 KLKB1 (0.44) KLKB1F2F10PRSS1PRSS2
SCHEMBL28944242 0.85 KLKB1 (0.39) KLKB1F10CARM1
SCHEMBL28777108 0.83 CARM1 (0.35) KLKB1F10CARM1
SCHEMBL28773942 0.83 KLKB1 (0.35) KLKB1F2F10CARM1
SCHEMBL28773931 0.81 CARM1 (0.36) KLKB1F10CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 — — CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 — — CN disclosed
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