Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 3/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256403 | 0.87 | HTT (0.68) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL14987117 | 0.83 | HTT (0.63) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL7627846 | 0.82 | MAPT (0.62) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL3347596 | 0.81 | HTT (0.60) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL13933220 | 0.81 | HTT (0.60) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL1851019 | 0.79 | HTT (0.59) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL1459408 | 0.79 | HTT (0.59) | HTTTSHRKMT2AMEN1ALOX15 | |
| SCHEMBL30046565 | 0.79 | HTT (0.59) | HTTTSHRKMT2AMEN1HDAC1 | |
| SCHEMBL16347168 | 0.79 | HTT (0.59) | HTTTSHRKMT2AMEN1HDAC1 | |
| SCHEMBL10053588 | 0.79 | HTT (0.59) | HTTTSHRKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101220058-B | Chirality and non-chirality PCN pincerlike palladium compound, synthesizing method and uses | UNIV ZHENGZHOU | 2012-01-25 | — | — | CN | disclosed |
| CN-101220058-A | Chirality and non-chirality PCN pincerlike palladium compound, synthesizing method and uses | UNIV ZHENGZHOU (CN) | 2008-07-16 | — | — | CN | disclosed |