Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10929981 | 0.72 | MAPT (0.77) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL11096597 | 0.71 | TP53 (0.50) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL10644380 | 0.69 | SMN1; SMN2 (0.46) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL16212102 | 0.68 | TP53 (0.47) | TP53RECQLSMN1; SMN2TSHRKDM4E | |
| SCHEMBL10736168 | 0.68 | TP53 (0.47) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL504941 | 0.68 | TP53 (0.61) | TP53RECQLSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7561032 | 0.68 | TP53 (0.56) | TP53RECQLSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL427764 | 0.67 | TP53 (0.85) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL11970980 | 0.67 | TP53 (0.55) | TP53RECQLSMN1; SMN2MAPTTSHR | |
| SCHEMBL11970977 | 0.67 | TP53 (0.55) | TP53RECQLSMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |