Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772262 | 0.97 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2769591 | 0.92 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2787887 | 0.89 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2791139 | 0.89 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2772803 | 0.88 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785816 | 0.88 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773077 | 0.88 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771100 | 0.87 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771440 | 0.86 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771245 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |