Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750956 | 0.93 | STAT3 (0.38) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL3584158 | 0.92 | SCN9A (0.38) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL27750945 | 0.92 | STAT3 (0.36) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL3575607 | 0.87 | CNR1 (0.40) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL27731176 | 0.85 | STAT3 (0.42) | STAT3CNR1SCN9ALPAR1LPAR5 | |
| SCHEMBL3575613 | 0.85 | SCN9A (0.39) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL3574442 | 0.84 | SCN9A (0.37) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL3574145 | 0.84 | SCN9A (0.39) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL3576581 | 0.83 | SCN9A (0.39) | STAT3CNR1SLC6A9KCNH2SCN9A | |
| SCHEMBL27750947 | 0.83 | STAT3 (0.36) | STAT3CNR1SLC6A9KCNH2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101379036-A | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |