SCHEMBL2773040

SCHEMBL2773040

CCOc1cc(C(=O)O)ccc1-c1ccc(C(=O)O)cc1OCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
POLB P06746 1/20 0.59
CASP6 P55212 1/20 0.59
TTR P02766 1/20 0.57
MRGPRX4 Q96LA9 1/20 0.53
LMNA P02545 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
TPMT P51580 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
GAA P10253 2/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1568236 0.92 TTR (0.61) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL1721733 0.90 TSHR (0.62) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL6536373 0.89 TSHR (0.60) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL410382 0.88 TSHR (0.56) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL411017 0.88 TSHR (0.56) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL177424 0.87 TSHR (0.83) TSHRPOLBCASP6MRGPRX4LMNA
SCHEMBL29882038 0.87 TSHR (0.83) TSHRPOLBCASP6MRGPRX4LMNA
SCHEMBL25289127 0.84 TSHR (0.68) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL2877001 0.84 TSHR (0.68) TSHRPOLBCASP6TTRMRGPRX4
SCHEMBL2355196 0.84 TSHR (0.68) TSHRPOLBCASP6TTRMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100323217-A1 MATERIAL FOR AN ELECTRICAL/ELECTRONIC PART AND ELECTRICAL/ELECTRONIC PART THE FURUKAWA ELECTRIC CO., LTD. (JP) 2010-12-23 US disclosed
EP-2248663-A1 MATERIAL FOR ELECTRICAL/ELECTRONIC COMPONENT AND ELECTRICAL/ELECTRONIC COMPONENT The Furukawa Electric Co., Ltd. (JP) 2010-11-10 EP disclosed
EP-0977209-B1 INSULATED WIRE FURUKAWA ELECTRIC CO LTD (JP) 2006-07-12 EP disclosed
US-6436537-B1 INSULATED WIRES WITH POLYAMIDEIMIDE COPOLYMERS THE FURUKAWA ELECTRIC CO., LTD. (JP) 2002-08-20 US disclosed
EP-0977209-A1 INSULATED WIRE THE FURUKAWA ELECTRIC CO., LTD. (JP) 2000-02-02 EP disclosed