Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149940 | 0.87 | KMT2A (0.70) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL1128303 | 0.84 | MAPT (1.00) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL9397206 | 0.84 | MAPT (0.79) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL11413547 | 0.82 | MAPT (0.75) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL8179196 | 0.82 | MAPT (0.71) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL29666347 | 0.81 | MAPT (1.00) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL149167 | 0.81 | MAPT (1.00) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL1150066 | 0.81 | MAPT (0.70) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL11833660 | 0.81 | MAPT (0.70) | MAPTPOLBATMMEN1KMT2A | |
| SCHEMBL1149826 | 0.81 | MAPT (0.73) | MAPTPOLBATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223139-B | 3-aminocarbazole compound, pharmaceutical composition containing the same, and method for producing the same | ACRAF | 2010-11-17 | — | — | CN | disclosed |
| CN-101223139-A | 3-aminocarbazole compound, pharmaceutical composition containing the same, and method for producing the same | ACRAF (IT) | 2008-07-16 | — | — | CN | disclosed |