SCHEMBL27730504

SCHEMBL27730504

COC(=O)C(CCCCN)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 8/20 0.61
ANPEP P15144 1/20 0.58
EPOR P19235 2/20 0.49
ATM Q13315 2/20 0.49
LNPEP Q9UIQ6 2/20 0.48
ERAP2 Q6P179 1/20 0.48
ERAP1 Q9NZ08 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 1/20 0.45
SSTR3 P32745 1/20 0.44
CNR2 P34972 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4911334 1.00 TLR2 (0.61) TLR2ANPEPEPORATMLNPEP
SCHEMBL6377386 0.88 TLR2 (0.57) TLR2ANPEPEPOR
Hydrochloric Acid SCHEMBL28916791 0.86 TLR2 (0.56) TLR2ANPEPEPOR
SCHEMBL3648738 0.86 TLR2 (0.54) TLR2ATMMEN1KMT2AL3MBTL1
SCHEMBL3650068 0.85 TLR2 (0.67) TLR2
SCHEMBL1976380 0.85 TLR2 (0.67) TLR2
Hydrochloric Acid SCHEMBL1880587 0.84 TLR2 (0.53) TLR2ATMMEN1KMT2AL3MBTL1
SCHEMBL28927258 0.83 TLR2 (0.53) TLR2ANPEPEPORSSTR3
SCHEMBL31669010 0.83 TLR2 (0.53) TLR2ANPEPEPORSSTR3
SCHEMBL23470280 0.82 ATM (0.54) ATMMEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101190911-A N-[2-(5,5-dimethyl-1,3-dioxan-2-yl)-ethyl]amino acid and its synthesis and application UNIV CAPITAL MEDICAL SCIENCES (CN) 2008-06-04 CN claimed
CN-100594213-C N-[2-(5,5-dimethyl-1,3-dioxan-2-yl)-ethyl]amino acid and its synthesis and application UNIV CAPITAL MEDICAL 2010-03-17 CN disclosed
CN-101190911-A N-[2-(5,5-dimethyl-1,3-dioxan-2-yl)-ethyl]amino acid and its synthesis and application UNIV CAPITAL MEDICAL SCIENCES (CN) 2008-06-04 CN disclosed