Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 18/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.66 |
| ▸ | GNRHR | P30968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158412 | 0.88 | CASR (0.84) | CASRNR1I2 | |
| SCHEMBL4150118 | 0.85 | CASR (0.63) | CASRNR1I2GNRHR | |
| SCHEMBL28777976 | 0.81 | CASR (0.68) | CASRNR1I2 | |
| SCHEMBL27751206 | 0.81 | CASR (0.68) | CASRNR1I2 | |
| SCHEMBL27751132 | 0.80 | CASR (0.64) | CASRNR1I2 | |
| SCHEMBL3344867 | 0.79 | CASR (1.00) | CASRNR1I2 | |
| SCHEMBL4148822 | 0.79 | CASR (1.00) | CASRNR1I2 | |
| SCHEMBL3421382 | 0.77 | CASR (0.82) | CASRNR1I2 | |
| SCHEMBL27751157 | 0.77 | CASR (0.69) | CASRNR1I2 | |
| SCHEMBL3344800 | 0.76 | CASR (0.74) | CASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360498-A | Calcilytic compounds | SMITHKLINE BEECHAM CORP (US) | 2009-02-04 | — | — | CN | disclosed |