Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL31267532 | 0.98 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Mucic Acid SCHEMBL17164506 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL14617612 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL16609840 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL8462892 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL13056936 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL15339348 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL19257183 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL21778048 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL16609838 | 0.97 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108308599-A | A kind of composite health care food of tonifying kidney and strengthening yang | 汪盛华 | 2018-07-24 | — | — | CN | claimed |
| CN-107028178-A | A kind of great talent particle | 汪盛华 | 2017-08-11 | — | — | CN | claimed |
| CN-101376110-A | Preparation of hydrogenation catalyst | CHINA PETROCHEMICAL CO LTD (CN) | 2009-03-04 | — | — | CN | claimed |
| CN-108308599-A | A kind of composite health care food of tonifying kidney and strengthening yang | 汪盛华 | 2018-07-24 | — | — | CN | disclosed |
| CN-108308599-A | A kind of composite health care food of tonifying kidney and strengthening yang | 汪盛华 | 2018-07-24 | — | — | CN | disclosed |
| CN-107028178-A | A kind of great talent particle | 汪盛华 | 2017-08-11 | — | — | CN | disclosed |
| CN-107028178-A | A kind of great talent particle | 汪盛华 | 2017-08-11 | — | — | CN | disclosed |
| CN-101462926-B | Method for complex catalytic decomposition of cyclohexyl hydrogen peroxide | DALIAN CHEMICAL PHYSICS INST | 2011-09-07 | — | — | CN | disclosed |
| CN-101376110-B | Preparation of hydrogenation catalyst | CHINA PETROCHEMICAL CO LTD | 2010-08-18 | — | — | CN | disclosed |
| CN-101462926-A | Method for complex catalytic decomposition of cyclohexyl hydrogen peroxide | DALIAN INST CHEM & PHYSICS (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101376110-A | Preparation of hydrogenation catalyst | CHINA PETROCHEMICAL CO LTD (CN) | 2009-03-04 | — | — | CN | disclosed |