Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 16/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SUV39H1 | O43463 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711994 | 0.76 | MAPK7 (0.40) | MAPK7KITSUV39H1PRMT1SMYD3 | |
| SCHEMBL27711985 | 0.76 | MAPK7 (0.40) | MAPK7KITSUV39H1PRMT1SMYD3 | |
| SCHEMBL5604689 | 0.75 | CYP1A2 (0.42) | KDM4EALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL27732137 | 0.74 | MAPK7 (0.37) | MAPK7KITSUV39H1PRMT1SMYD3 | |
| SCHEMBL21332116 | 0.71 | MAPK7 (0.47) | MAPK7KIT | |
| SCHEMBL21332328 | 0.71 | HSP90AB1 (0.41) | MAPK7KIT | |
| SCHEMBL27711987 | 0.69 | MAPK7 (0.37) | MAPK7KIT | |
| SCHEMBL3570966 | 0.69 | NPC1 (0.47) | ALDH1A1CYP1A2KIT | |
| SCHEMBL3563859 | 0.68 | MAPK7 (0.44) | MAPK7KIT | |
| SCHEMBL3570195 | 0.68 | MAPK7 (0.53) | MAPK7KDM4ECYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243065-A | Intermediates for the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related synthetic methods | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |