Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 8/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733283 | 1.00 | MEN1 (0.44) | MEN1KMT2APARP1PARP10LMNA | |
| SCHEMBL28775025 | 0.85 | MEN1 (0.45) | MEN1KMT2APARP1PARP10LMNA | |
| SCHEMBL27733278 | 0.85 | PPARG (0.46) | — | |
| SCHEMBL27733280 | 0.85 | PPARG (0.46) | — | |
| SCHEMBL27753813 | 0.78 | F7 (0.46) | MEN1KMT2APARP1PARP10ALDH1A1 | |
| SCHEMBL3856668 | 0.78 | HPGD (0.39) | MEN1KMT2APARP1PARP10LMNA | |
| SCHEMBL3857805 | 0.76 | PARP1 (0.39) | MEN1KMT2APARP1PARP10PARP14 | |
| SCHEMBL3858646 | 0.73 | HPGD (0.41) | LMNAHPGD | |
| SCHEMBL3863063 | 0.72 | CA12 (0.41) | PARP1PARP10LMNA | |
| SCHEMBL3856730 | 0.68 | HPGD (0.41) | MEN1KMT2APARP1PARP10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101389613-B | Macrocyclic factor viia inhibitors useful as anticoagulants | BRISTOL MYERS SQUIBB CO | 2011-10-12 | — | — | CN | disclosed |
| CN-101389613-A | Macrocyclic factor viia inhibitors useful as anticoagulants | BRISTOL MYERS SQUIBB CO (US) | 2009-03-18 | — | — | CN | disclosed |