Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733789 | 0.91 | PPARG (0.59) | PPARGPPARANPSR1S1PR1RECQL | |
| SCHEMBL27713297 | 0.84 | PPARG (0.50) | PPARGPPARANPSR1NOD1PPARD | |
| SCHEMBL27733700 | 0.82 | RECQL (0.56) | PPARGPPARARECQLNOD1PPARD | |
| SCHEMBL27713308 | 0.77 | PPARG (0.40) | PPARGPPARARECQLPPARDPTGDR2 | |
| SCHEMBL27733713 | 0.76 | PPARG (0.46) | PPARGPPARARECQLNOD1PPARD | |
| SCHEMBL3527611 | 0.76 | PPARG (0.73) | PPARGPPARARORCPPARD | |
| SCHEMBL27713335 | 0.76 | PPARG (0.58) | PPARGPPARARECQLNOD1PPARD | |
| SCHEMBL30629080 | 0.75 | PPARG (0.56) | PPARGPPARARORCS1PR1NOD1 | |
| SCHEMBL27713493 | 0.75 | PPARG (0.43) | PPARGPPARARECQLPPARDMAPT | |
| SCHEMBL27733864 | 0.75 | PPARG (0.59) | PPARGPPARARECQLNOD1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |