Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.48 |
| ▸ | PPARD | Q03181 | 13/20 | 0.48 |
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733848 | 0.95 | PPARG (0.54) | PPARGPPARDPPARAHSD11B1 | |
| SCHEMBL27733822 | 0.88 | PPARG (0.45) | PPARGPPARDPPARA | |
| SCHEMBL27713307 | 0.87 | PPARG (0.60) | PPARGPPARDPPARA | |
| SCHEMBL27733703 | 0.83 | PPARG (0.48) | PPARGPPARDPPARA | |
| SCHEMBL28775104 | 0.83 | PPARG (0.52) | PPARGPPARDPPARA | |
| SCHEMBL27713325 | 0.82 | PPARG (0.68) | PPARGPPARDPPARA | |
| SCHEMBL27713685 | 0.82 | PPARG (0.59) | PPARGPPARDPPARA | |
| SCHEMBL3525462 | 0.82 | PPARG (0.67) | PPARGPPARDPPARA | |
| SCHEMBL27713336 | 0.81 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL27733653 | 0.81 | PPARG (0.47) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |