Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.66 |
| ▸ | CHUK | O15111 | 6/20 | 0.66 |
| ▸ | BTK | Q06187 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713513 | 0.92 | IKBKB (0.66) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL552457 | 0.91 | IKBKB (0.69) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551301 | 0.89 | IKBKB (0.73) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551975 | 0.88 | IKBKB (0.72) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551618 | 0.88 | IKBKB (0.71) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551898 | 0.88 | IKBKB (0.71) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL27713523 | 0.88 | IKBKB (0.71) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL552793 | 0.88 | IKBKB (0.71) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551686 | 0.87 | IKBKB (0.70) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL552901 | 0.86 | IKBKB (0.76) | IKBKBCHUKBTKAURKAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101247804-A | chemical compound | SMITHKLINE BEECHAM CORP (US) | 2008-08-20 | — | — | CN | claimed |
| CN-101247804-B | chemical compound | SMITHKLINE BEECHAM CORP | 2012-09-26 | — | — | CN | disclosed |
| CN-101247804-A | chemical compound | SMITHKLINE BEECHAM CORP (US) | 2008-08-20 | — | — | CN | disclosed |