Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.53 |
| ▸ | EGFR | P00533 | 11/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.53 |
| ▸ | PRKDC | P78527 | 9/20 | 0.53 |
| ▸ | ABL1 | P00519 | 8/20 | 0.53 |
| ▸ | HCK | P08631 | 8/20 | 0.53 |
| ▸ | KDR | P35968 | 8/20 | 0.53 |
| ▸ | MTOR | P42345 | 8/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 8/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | CSK | P41240 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953587 | 0.92 | SRC (0.57) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16762572 | 0.85 | SRC (0.49) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4977239 | 0.85 | SRC (0.49) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2956346 | 0.85 | SRC (0.63) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2961978 | 0.84 | SRC (0.59) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL27733964 | 0.84 | SRC (0.56) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2959431 | 0.83 | EGFR (0.56) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2962222 | 0.83 | EGFR (0.56) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2960030 | 0.82 | IGF1R (0.57) | SRCEGFRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4979594 | 0.82 | SRC (0.48) | SRCEGFRPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101389630-A | Protein kinase inhibitors | ABBOTT LAB (US) | 2009-03-18 | — | — | CN | disclosed |