Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.73 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.65 |
| ▸ | PREP | P48147 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734379 | 0.99 | DPP4 (0.74) | DPP4DPP8DPP7PREP | |
| Hydrochloric Acid SCHEMBL27960031 | 0.98 | DPP4 (0.73) | DPP4DPP8DPP7PREP | |
| Oxalic Acid SCHEMBL27754785 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP7 | |
| Oxalic Acid SCHEMBL27734387 | 0.86 | DPP4 (0.76) | DPP4DPP8DPP7 | |
| Oxalic Acid SCHEMBL27960032 | 0.86 | DPP4 (0.76) | DPP4DPP8DPP7 | |
| SCHEMBL27734271 | 0.85 | DPP4 (0.76) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL28775256 | 0.84 | DPP4 (0.74) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL27960030 | 0.84 | DPP4 (0.74) | DPP4DPP8DPP7 | |
| Oxalic Acid SCHEMBL27960037 | 0.83 | DPP4 (0.66) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27734347 | 0.82 | DPP4 (0.65) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850330-B | Method for preparing N-substituted pyrrolidine derivative through bromination | DIAO PHARMACEUTICAL GROUP CO., LTD., CHENGDU (CN) | 2014-10-15 | — | — | CN | disclosed |
| CN-102838589-B | Method for preparing N substituted pyrrolidine derivative through acylation of methyl sulfone chloride | CHENGDU DIAO PHARMACY GROUP CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102850330-A | Method for preparing N-substituted pyrrolidine derivative through bromination | CHENGDU DIAO PHARMACY GROUP CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102838589-A | Method for preparing N substituted pyrrolidine derivative through acylation of methyl sulfone chloride | CHENGDU DIAO PHARMACY GROUP CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101397294-B | N-substituted pyrrolidine derivatives and use thereof | CHENGDU DIAO PHARMACY GROUP CO LTD | 2012-12-05 | — | — | CN | disclosed |
| CN-101397294-A | N-substituted pyrrolidine derivatives and use thereof | CHENGDU DIAO PHARMACEUTICAL GR (CN) | 2009-04-01 | — | — | CN | disclosed |