Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522449 | 1.00 | GRIK1 (0.43) | GRIK1TAAR1DPP4MC4RMC3R | |
| SCHEMBL20438857 | 0.86 | GRIK1 (0.54) | GRIK1LMNA | |
| SCHEMBL1586370 | 0.84 | SLC7A5 (0.49) | GRIK1TAAR1LMNA | |
| SCHEMBL27734517 | 0.84 | GRIK1 (0.44) | GRIK1S1PR1 | |
| SCHEMBL1586369 | 0.84 | SLC7A5 (0.49) | GRIK1TAAR1LMNA | |
| SCHEMBL27734516 | 0.84 | GRIK1 (0.44) | GRIK1S1PR1 | |
| SCHEMBL27734651 | 0.83 | PPARG (0.51) | GRIK1TAAR1DPP4 | |
| SCHEMBL27734653 | 0.83 | PPARG (0.51) | GRIK1TAAR1DPP4 | |
| SCHEMBL29032086 | 0.82 | GRIK1 (0.61) | GRIK1LMNANPC1RAB9AS1PR1 | |
| SCHEMBL27754701 | 0.82 | GRIK1 (0.61) | GRIK1LMNANPC1RAB9AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |