Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641890 | 0.97 | — | — | |
| SCHEMBL27986801 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL11861848 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| Fluoride SCHEMBL27987761 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| Hydrochloric Acid SCHEMBL6673110 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL912414 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL912568 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL28772165 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL911353 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 | |
| SCHEMBL28141562 | 0.93 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102037029-B | Functionalized polymers and processes for making same | BRIDGESTONE CORP | 2013-01-16 | — | — | CN | disclosed |
| CN-101563398-B | Branched polymers and methods of synthesis and use thereof | BRIDGESTONE CORP | 2012-10-24 | — | — | CN | disclosed |
| CN-101418054-B | Functionalized polymers | BRIDGESTONE CORP | 2012-08-15 | — | — | CN | disclosed |
| CN-102037029-A | Functionalized polymers and processes for making same | BRIDGESTONE CORP | 2011-04-27 | — | — | CN | disclosed |
| CN-101184794-B | Enhancing interactivity between amine-functionalized polymers and particulate fillers | BRIDGESTONE CORP | 2011-04-13 | — | — | CN | disclosed |
| CN-101563398-A | Branched polymers and methods of synthesis and use thereof | BRIDGESTONE CORP (JP) | 2009-10-21 | — | — | CN | disclosed |
| CN-101418054-A | Functionalized polymers | BRIDGESTONE CORP (JP) | 2009-04-29 | — | — | CN | disclosed |
| CN-101184794-A | Enhancing interactivity between amine-functionalized polymers and particulate fillers | BRIDGESTONE CORP (JP) | 2008-05-21 | — | — | CN | disclosed |