Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.64 |
| ▸ | PDE4A | P27815 | 17/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832576 | 0.86 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL23717240 | 0.85 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL27756254 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL16409548 | 0.82 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28168416 | 0.81 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL16411001 | 0.81 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL27802861 | 0.81 | NPC1 (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1143632 | 0.80 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL132715 | 0.80 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL1143518 | 0.79 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |