Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735661 | 0.88 | CCR1 (0.51) | CCR1CYP2C19KCNH2ALK | |
| SCHEMBL1637582 | 0.85 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3632308 | 0.82 | CCR1 (0.46) | CCR1ALK | |
| SCHEMBL3468956 | 0.77 | CCR1 (0.59) | CCR1CYP2C19KCNH2 | |
| SCHEMBL12726256 | 0.75 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL14723929 | 0.75 | CCR1 (0.73) | CCR1CYP2C19KCNH2 | |
| SCHEMBL28780517 | 0.73 | CCR1 (0.54) | CCR1CYP2C19KCNH2 | |
| SCHEMBL27764766 | 0.73 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL28812576 | 0.73 | CCR1 (0.58) | CCR1KCNH2ALK | |
| SCHEMBL27786535 | 0.73 | CCR1 (0.50) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-B | Azaindazole compounds and methods of use | CHEMOCENTRYX INC | 2012-11-07 | — | — | CN | disclosed |
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |