SCHEMBL27735944

SCHEMBL27735944

CC(O)CN.Cc1c(C(=O)O)cccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
MYC P01106 2/20 0.44
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
HMGB1 P09429 1/20 0.42
ALOX15 P16050 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
PTGER1 P34995 1/20 0.40
MEN1 O00255 1/20 0.40
AKR1B10 O60218 1/20 0.40
TRPA1 O75762 1/20 0.40
ABCB11 O95342 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL28803562 0.87 TSHR (0.47) TSHRMYCALDH1A1KDM4EHSD17B10
Isopropyl Alcohol SCHEMBL28791730 0.86 TSHR (0.53) TSHRMYCALDH1A1KDM4EHSD17B10
SCHEMBL28158629 0.86 TSHR (0.44) TSHRMYCALDH1A1KDM4EHSD17B10
SCHEMBL27469215 0.85 TSHR (0.46) TSHRMYCALDH1A1KDM4EHSD17B10
Benzene SCHEMBL28200229 0.84 TSHR (0.52) TSHRMYCALDH1A1KDM4EHSD17B10
Isobutane SCHEMBL27746314 0.84 TSHR (0.55) TSHRMYCALDH1A1KDM4EHSD17B10
Hydrazine SCHEMBL28166056 0.82 TSHR (0.57) TSHRMYCALDH1A1KDM4EHSD17B10
SCHEMBL756585 0.82 TSHR (0.61) TSHRMYCALDH1A1KDM4EHSD17B10
Ammonia Solution, Strong SCHEMBL28842683 0.82 TSHR (0.41) TSHRMYCALDH1A1KDM4EHSD17B10
SCHEMBL27703149 0.82 TSHR (0.61) TSHRMYCALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101252847-B Improved flavour compositions QUEST INT SERV BV 2012-05-23 CN disclosed
CN-101252847-A Improved flavour compositions QUEST INT SERV BV (NL) 2008-08-27 CN disclosed