SCHEMBL27736611

SCHEMBL27736611

c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1cc(-c3cccc4c5nc6nc(nc7[nH]c(nc8nc(nc([nH]5)c34)-c3ccccc3-8)c3ccccc73)-c3ccccc3-6)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
APEX1 P27695 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALK Q9UM73 3/20 0.35
PDK2 Q15119 2/20 0.33
PDK4 Q16654 2/20 0.33
CDK4 P11802 5/20 0.33
CCND1 P24385 5/20 0.33
CA5A P35218 1/20 0.33
MAPT P10636 1/20 0.32
GSK3B P49841 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
ACVR1 Q04771 1/20 0.31
CCNB2 O95067 1/20 0.31
CCNE2 O96020 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28193019 0.87 TDP1 (0.47) MEN1THRBAPEX1RECQLBLM
SCHEMBL5414474 0.87 CLK4 (0.41) MEN1THRBAPEX1RECQLBLM
SCHEMBL7455206 0.86 MEN1 (0.40) MEN1THRBAPEX1RECQLBLM
SCHEMBL27682830 0.84 KDR (0.41) MEN1THRBAPEX1RECQLBLM
SCHEMBL27852228 0.84 BLM (0.49) MEN1THRBAPEX1RECQLBLM
SCHEMBL7193083 0.83 TDP1 (0.40) MEN1THRBAPEX1RECQLBLM
SCHEMBL769522 0.82 BLM (0.48) MEN1THRBAPEX1RECQLBLM
SCHEMBL27501031 0.82 MEN1 (0.36) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL3316411 0.81 MEN1 (0.49) MEN1THRBAPEX1RECQLBLM
SCHEMBL27755029 0.81 GSK3B (0.39) MEN1THRBAPEX1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110488580-A Electrophtography photosensor manufacturing method, coating fluid and Electrophtography photosensor KYOCERA DOCUMENT SOLUTIONS INC 2019-11-22 CN disclosed
CN-110488579-A Manufacturing method, coating fluid, photoreceptor and the image forming apparatus of photoreceptor KYOCERA DOCUMENT SOLUTIONS INC 2019-11-22 CN disclosed
CN-106810498-B Naphthylimine derivative and electrophotographic photoreceptor 京瓷办公信息系统株式会社 2019-09-24 CN disclosed
CN-110178088-A Electrophotographic photoreceptor 京瓷办公信息系统株式会社 2019-08-27 CN disclosed
CN-110095958-A Photoreceptor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-08-06 CN disclosed
CN-110095956-A Photoreceptor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-08-06 CN disclosed
CN-110095957-A Photoreceptor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-08-06 CN disclosed
CN-110088691-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2019-08-02 CN disclosed
CN-110088690-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2019-08-02 CN disclosed
CN-109803994-A Polyarylate resin and Electrophtography photosensor 京瓷办公信息系统株式会社 2019-05-24 CN disclosed
CN-107643658-A Electrophotographic photoreceptor 京瓷办公信息系统株式会社 2018-01-30 CN disclosed
CN-106810498-A Naphthylimine derivative and electrophotographic photoreceptor 京瓷办公信息系统株式会社 2017-06-09 CN disclosed
CN-102356354-B Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2013-08-07 CN disclosed
CN-102405443-B Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2013-07-31 CN disclosed
CN-101878453-B Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2012-06-27 CN disclosed
CN-102405443-A Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2012-04-04 CN disclosed
CN-102356354-A Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2012-02-15 CN disclosed
CN-101275085-B Combined method for gasoline desulfurization CHINA PETROLEUM & CHEMICAL 2012-01-25 CN disclosed
CN-101878453-A Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2010-11-03 CN disclosed
CN-101275085-A Combined method for gasoline desulfurization CHINA PETROCHEMICAL CORP (CN) 2008-10-01 CN disclosed