⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28851463 | 0.97 | — | — | |
| SCHEMBL12220162 | 0.86 | MEN1 (0.60) | — | |
| SCHEMBL13033257 | 0.86 | MEN1 (0.60) | — | |
| SCHEMBL13033260 | 0.86 | MEN1 (0.60) | — | |
| SCHEMBL13033256 | 0.86 | MEN1 (0.60) | — | |
| SCHEMBL13033259 | 0.86 | MEN1 (0.60) | — | |
| SCHEMBL7023116 | 0.85 | — | — | |
| SCHEMBL15187041 | 0.83 | MEN1 (0.77) | — | |
| SCHEMBL12799428 | 0.83 | MEN1 (0.78) | — | |
| SCHEMBL15856109 | 0.81 | MEN1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159795-A1 | THERAPEUTIC CONJUGATES WITH SULFATED DENDRIMERS FOR INTRACELLULAR TARGETING | ICD-Therapeutics GmbH (DE) | 2023-04-05 | — | — | EP | claimed |
| CN-111615528-A | Dendrimer delivery systems and methods of use thereof | 约翰霍普金斯大学 | 2020-09-01 | — | — | CN | claimed |
| US-7560460-B2 | Substituted piperazines and methods of use | AMGEN INC. (US) | 2009-07-14 | — | — | US | claimed |
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | claimed |
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |
| US-20070265248-A1 | Substituted piperazines and methods of use | AMGEN INC. (US) | 2007-11-15 | — | — | US | claimed |
| US-7115607-B2 | Substituted piperazinyl amides and methods of use | AMGEN INC. (US) | 2006-10-03 | — | — | US | claimed |
| US-6977264-B2 | Substituted piperidines and methods of use | AMGEN INC. (US) | 2005-12-20 | — | — | US | claimed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | claimed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | claimed |
| EP-0124274-B1 | ELECTRON BEAM SENSITIVE MIXTURE RESIST | GAF CORPORATION (US) | 1988-06-22 | — | — | EP | claimed |
| EP-0088977-B1 | ELECTRON BEAM SENSITIVE RESIST | GAF CORPORATION (US) | 1988-06-01 | — | — | EP | claimed |
| EP-0126652-B1 | ELECTRON BEAM SENSITIVE MIXTURE RESIST | GAF CORPORATION (US) | 1987-04-22 | — | — | EP | claimed |
| EP-0126652-A1 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-28 | — | — | EP | claimed |
| EP-0124274-A2 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-07 | — | — | EP | claimed |
| US-4448875-A | HALF-ESTER OR -AMIDE OF ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER | GAF CORPORATION (US) | 1984-05-15 | — | — | US | claimed |
| EP-0088977-A2 | Electron beam sensitive resist | GAF CORPORATION (US) | 1983-09-21 | — | — | EP | claimed |
| US-4375398-A | CROSSLINKING, VINYL ETHER | GAF CORPORATION (US) | 1983-03-01 | — | — | US | claimed |