Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 15/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2266026 | 0.85 | PARP1 (0.44) | PARP1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2263871 | 0.84 | PARP1 (0.42) | PARP1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2264952 | 0.84 | PARP1 (0.43) | PARP1JAK2JAK3JAK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2265597 | 0.83 | PARP1 (0.41) | PARP1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2265228 | 0.81 | PARP1 (0.44) | PARP1PARP2 | |
| Trifluoroacetic Acid SCHEMBL27738194 | 0.80 | PARP1 (0.40) | PARP1L3MBTL1PARP2 | |
| Ammonia Solution, Strong SCHEMBL28920665 | 0.78 | PARP1 (0.44) | PARP1 | |
| SCHEMBL4768133 | 0.78 | PARP1 (0.50) | PARP1PARP2 | |
| SCHEMBL30157780 | 0.77 | PARP1 (0.47) | PARP1PARP2 | |
| Trifluoroacetic Acid SCHEMBL2264136 | 0.76 | PARP1 (0.40) | PARP1JAK2JAK1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288892-B | Use of poly ADP-ribose polymerase inhibitors against coronaviruses | 甫康（上海）健康科技有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113288892-A | Application of poly ADP ribose polymerase inhibitor in resisting coronavirus | 甫康（上海）健康科技有限责任公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-101415686-B | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2013-03-13 | — | — | CN | disclosed |
| CN-101415686-A | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-04-22 | — | — | CN | disclosed |