SCHEMBL2773832

SCHEMBL2773832

C=CCCC1=NC(C)C(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6702045 0.82
SCHEMBL6135974 0.79
SCHEMBL6699251 0.77
SCHEMBL6136392 0.77
SCHEMBL6698320 0.74
SCHEMBL14066057 0.73
SCHEMBL968425 0.67
SCHEMBL2876279 0.61
SCHEMBL13270244 0.58 PRSS1 (0.30)
SCHEMBL967961 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646240-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING Bausch + Lomb Ireland Limited (IE) 2025-11-12 EP disclosed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
WO-2024146878-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING BAUSCH + LOMB IRELAND LIMITED (IE) 2024-07-11 WO disclosed
EP-2370113-B1 PACKAGING SOLUTIONS BAUSCH & LOMB (US) 2013-12-11 EP disclosed
US-8534031-B2 Packaging solutions BAUSCH & LOMB INCORPORATED (US) 2013-09-17 US disclosed
US-8377126-B2 Renewable polymeric lens coating BAUSCH & LOMB INCORPORATED (US) 2013-02-19 US disclosed
US-20100162663-A1 Packaging Solutions ORAPHARMA, INC. 2010-07-01 US disclosed
US-20100168851-A1 Surface Modified Biomedical Devices ISTA PHARMACEUTICALS 2010-07-01 US disclosed
US-20100168855-A1 Method of Applying Renewable Polymeric Lens Coating BAUSCH HEALTH COMPANIES INC. (CA) 2010-07-01 US disclosed
US-20070132121-A1 Method of cleaning molds using super-cooled fluids BAUSCH & LOMB INCORPORATED 2007-06-14 US disclosed
US-20040001181-A1 Lens with colored portion and coated surface BAUSCH & LOMB INCORPORATED 2004-01-01 US disclosed
US-20030235604-A1 Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers BAUSCH & LOMB INCORPORATED (US) 2003-12-25 US disclosed
US-20030224185-A1 Surface treatment for silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating BAUSCH & LOMB INCORPORATED 2003-12-04 US disclosed
US-6638563-B2 Comprises dimethyacrylamide-octafluoropentylmethacrylate-glycidyl methacrylate for enhancing biocompatibility/ hydrophilicity of surfaces of silicone contact lenses (overnight and continuous wear) and medical implants BAUSCH & LOMB INCORPORATED 2003-10-28 US disclosed
US-6630243-B2 Sequentially subjecting the surface of the lens to plasma polymerization in a hydrocarbon-containing atmosphere and then covalently attaching a preformed hydrophilic polymer to the surface of the carbon coating. BAUSCH & LOMB INCORPORATED 2003-10-07 US disclosed
US-6599559-B1 Biocompatible coating for hydrogel contact lens; comfortable for a longer period of time; tear wettable; oxygen permeable; long term continuous wear without adverse effects to cornea BAUSCH & LOMB INCORPORATED 2003-07-29 US disclosed
US-20030068433-A1 Method for applying polymeric lens coating BAUSCH & LOMB INCORPORATED 2003-04-10 US disclosed
US-20020120084-A1 Surface treatment of silicone medical devices with reactive hydrophilic polymers VALINT PAUL L (US) 2002-08-29 US disclosed
US-6440571-B1 TO INCREASE ITS BIOCOMPATIBILITY OR HYDROPHILICITY; MEDICAL DEVICES SUCH AS CONTACT LENSES BAUSCH & LOMB INCORPORATED 2002-08-27 US disclosed
US-20020102415-A1 SURFACE TREATMENT OF SILICONE HYDROGEL CONTACT LENSES COMPRISING HYDROPHILIC POLYMER CHAINS ATTACHED TO AN INTERMEDIATE CARBON COATING BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-08-01 US disclosed