Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773470 | 0.98 | TSHR (0.67) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL10834721 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL632341 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL5392962 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL3120781 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL11795597 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL180289 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL28083294 | 0.90 | TSHR (0.84) | TSHREPHX2ALDH1A1LMNADGKA | |
| SCHEMBL153651 | 0.89 | TSHR (0.77) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL11131759 | 0.87 | TSHR (0.74) | TSHREPHX2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174966-A1 | OPTICAL MATERIAL AND OPHTHALMIC LENS MADE OF THE SAME | Menicon Co., Ltd. (JP) | 2010-04-14 | — | — | EP | disclosed |