Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738870 | 1.00 | CYP3A4 (0.67) | CYP3A4 | |
| SCHEMBL18715751 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL21946528 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL2736036 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL2736101 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL2736102 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL2736103 | 0.91 | CYP3A4 (0.73) | CYP3A4 | |
| SCHEMBL18715877 | 0.89 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL14123813 | 0.89 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL271601 | 0.89 | CYP3A4 (0.83) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432129-A | Novel compounds that are useful for improving pharmacokinetics | ABBOTT LAB (US) | 2009-05-13 | — | — | CN | disclosed |