SCHEMBL27738993

SCHEMBL27738993

CCC(Oc1ccc(F)c(-c2ccccc2)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.47
PPARA Q07869 4/20 0.47
FFAR1 O14842 1/20 0.46
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738825 0.83 PPARD (0.46) PPARDPPARAFFAR1PPARG
SCHEMBL3742785 0.77 PPARD (0.43) PPARDPPARAFFAR1PPARG
SCHEMBL3747883 0.77 PPARD (0.44) PPARDPPARAFFAR1PPARG
SCHEMBL3739510 0.77 PPARD (0.40) PPARDPPARAFFAR1PPARG
SCHEMBL4822468 0.77 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL4831975 0.77 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL4822474 0.77 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL5847998 0.76 PPARD (0.48) PPARDPPARAPPARG
SCHEMBL27738971 0.76 PPARD (0.42) PPARDPPARAFFAR1PPARG
SCHEMBL3743524 0.76 PPARD (0.45) PPARDPPARAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101273036-A Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals SANOFI AVENTIS (FR) 2008-09-24 CN disclosed