Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.70 |
| ▸ | PRKCD | Q05655 | 16/20 | 0.70 |
| ▸ | LYN | P07948 | 9/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.64 |
| ▸ | PRKCB | P05771 | 1/20 | 0.64 |
| ▸ | PRKCH | P24723 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771753 | 0.91 | PRKCQ (0.72) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5514708 | 0.82 | PRKCQ (0.82) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5525540 | 0.82 | PRKCQ (0.47) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL4941352 | 0.79 | PRKCQ (0.60) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL4947443 | 0.78 | PRKCQ (1.00) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL4954397 | 0.78 | PRKCQ (0.73) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5516133 | 0.74 | PRKCQ (0.83) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5517796 | 0.73 | PRKCQ (0.81) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5522448 | 0.72 | PRKCQ (0.81) | PRKCQPRKCDLYNLCKPRKCB | |
| SCHEMBL5514663 | 0.72 | PRKCQ (0.80) | PRKCQPRKCDLYNLCKPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273047-A | Thieno [2, 3-B ] pyridine-5-carbonitriles as protein kinase inhibitors | WYETH CORP (US) | 2008-09-24 | — | — | CN | disclosed |