Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022461 | 0.89 | CA1 (0.60) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4214499 | 0.89 | CA1 (0.60) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8083186 | 0.88 | FFAR1 (0.57) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28352734 | 0.86 | FFAR1 (0.56) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28353258 | 0.86 | APP (0.58) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28353255 | 0.86 | FFAR1 (0.56) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28356528 | 0.85 | FFAR1 (0.55) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14958068 | 0.85 | KCNH2 (0.49) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28353254 | 0.85 | FFAR1 (0.55) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28353226 | 0.83 | GRM5 (0.49) | FFAR1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117845235-A | Preparation method of cis-stilbene compound | 深圳市环保科技集团股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-110372653-B | Selenylation benzofuran compound and synthesis method thereof | 温州大学 | 2022-11-15 | — | — | CN | claimed |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | BioMendics, LLC (US) | 2022-06-07 | — | — | US | claimed |
| CN-110791775-B | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-05 | — | — | CN | claimed |
| CN-110760877-B | Method for continuously preparing 2-aryl-3-halogenated-benzofuran compound by using electrochemical microchannel reaction device | 南京工业大学 | 2021-01-29 | — | — | CN | claimed |
| CN-111526873-A | Substituted tolanes for regulating microbial colonization | 生物曼迪克斯有限责任公司 | 2020-08-11 | — | — | CN | claimed |
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2020-07-02 | — | — | US | claimed |
| EP-3658128-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | Biomendics, LLC (US) | 2020-06-03 | — | — | EP | claimed |
| CN-110791775-A | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2020-02-14 | — | — | CN | claimed |
| CN-110760877-A | Method for continuously preparing 2-aryl-3-halogenated-benzofuran compound by using electrochemical microchannel reaction device | 南京工业大学 | 2020-02-07 | — | — | CN | claimed |
| WO-2019023425-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | BioMendics, LLC (US) | 2019-01-31 | — | — | WO | claimed |
| WO-2024261504-A1 | BENZOFURAN-3-CARBOXYLIC ACID AMIDES AND BENZOFURAN-3- CARBONYL-BENZAMIDES, METHOD FOR THEIR PRODUCTION WITH HIGH SELECTIVITY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PÉCSI TUDOMÁNYEGYETEM (HU) | 2024-12-26 | — | — | WO | disclosed |
| US-20240237383-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SFC CO., LTD. (KR) | 2024-07-11 | — | — | US | disclosed |
| CN-111856878-B | Resist underlayer composition and method for forming pattern using the same | 罗门哈斯电子材料有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117845235-A | Preparation method of cis-stilbene compound | 深圳市环保科技集团股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-7642391-B1 | Palladium-catalyzed coupling of aryl halides with alkynes | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7105374-B1 | Memory cell containing copolymer containing diarylacetylene portion | SPANSION LLC (US) | 2006-09-12 | — | — | US | disclosed |
| EP-0171209-B1 | ACETYLENIC PHENOXYPROPANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4652584-A | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension | MCNEILAB, INC. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0171209-A1 | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension | McNeilab, Inc. (US) | 1986-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | LMAN1, DPM1, DSTN | FFAR1 350/4885MEN1 3825/4885KMT2A 3977/4885 |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | LMAN1, DPM1, DSTN | FFAR1 350/4885MEN1 3825/4885KMT2A 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.