Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892968 | 0.98 | TDP1 (0.50) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL2122837 | 0.98 | TDP1 (0.50) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL5801967 | 0.98 | TDP1 (0.50) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL27648828 | 0.91 | PDE4A (0.48) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL27844168 | 0.84 | TDP1 (0.55) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL28448089 | 0.84 | TDP1 (0.55) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL19951539 | 0.84 | TDP1 (0.55) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL2341187 | 0.84 | TDP1 (0.55) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL2337822 | 0.84 | TDP1 (0.55) | TDP1PDE4ALMNAL3MBTL1USP2 | |
| SCHEMBL21495088 | 0.83 | TDP1 (0.52) | TDP1PDE4ALMNAL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101431978-A | Water-dispersible patch containing an active agent for dermal delivery | EASTMAN CHEM CO (US) | 2009-05-13 | — | — | CN | disclosed |
| CN-101432333-A | Water dispersible films for delivery of active agents to the epidermis | EASTMAN CHEM CO (US) | 2009-05-13 | — | — | CN | disclosed |